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Whipple Disease Confined to the Central Nervous System in Childhood
AJNR 17:1589-1591, Duprez,T.P.J.,et al, 1996
See this aricle in Pubmed

Article Abstract
In a case of pediatric Whipple disease confined to the central nervous system,white matter lesions initially appeared as areas of very low signal intensity on T1-weighted MR images and as areas of hyperintensity on proton density-weighted and T2-weighted images,and showed slight peripheral enhancement on delayed contrast-enhanced T1-weighted images.On MRi studies obtained 3 and 6 months after antibiotic therapy,the lesions had decreased in size and no longer enhanced.They became progressively less hypointense on T1-weighted images and less hyperintense on T2- weighted images.
 
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children
dementia
dementia,childhood
dementia,treatment of
gadolinium
intellectual deficit
MRI
MRI,abnormal
MRI,contrast enhanced
treatment of neurologic disorder
Whipple's disease
white matter disease

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